Research Interests

FOUNDATION Models

LLM Reasoning & Post-training

Data-efficient post-training, reinforcement learning, and uncertainty quantification for more capable and reliable LLM reasoning.

Post-trainingReasoningReinforcement learning

AgentIC AI

LLM Agents & RAG

LLM agents, retrieval, memory, and tool use for building reliable and grounded systems for real-world applications.

LLM agentsRAGAgent memory

Graph Machine Learning

Machine Learning for Graphs & Dynamical Systems

Machine learning for graph-structured data and dynamical systems to solve real-world problems.

Graph learningDynamical systemsTrustworthy AI

AI for Science

AI for Computational Biology & Healthcare

AI-driven methods for genomics, molecules, biomedical and healthcare applications.

BioinformaticsGenomicsHealthcare

If you are interested in my research or would like to work with me (including onsite/remote internship/collaboration), please feel free to email me!

News

  • Invited as an Area Chair for KDD 2026.
  • Invited as an Area Chair for ACL ARR 2026 January.
  • Received the Distinguished Area Chair Certificate from ECML-PKDD 2025.

Selected Publications

  • Zhiping Xiao, Yusheng Zhao, Qixin Zhang, Jiaye Xie, Wanjia Zhao, Weizhi Zhang, Xiao Luo, Philip S. Yu, and Ming Zhang, “Sample Lottery: Unsupervised Discovery of Critical Instances for LLM Reasoning,” In International Conference on Learning Representations (ICLR), 2026.
  • Xiaoda Wang, Kaiqiao Han, Yuhao Xu, Xiao Luo, Yizhou Sun, Wei Wang, and Carl Yang, “SE-Diff: Simulator and Experience Enhanced Diffusion Model for Comprehensive ECG Generation,” In International Conference on Learning Representations (ICLR), 2026.
  • Wanjia Zhao, Qinwei Ma, Jingzhe Shi, Shirley Wu, Jiaqi Han, Yijia Xiao, Si-Yuan Chen, Xiao Luo, Ludwig Schmidt, and James Zou, “PRISM-Physics: Causal DAG-Based Process Evaluation for Physics Reasoning,” In International Conference on Learning Representations (ICLR), 2026.
  • Yiyang Gu, Wenrui Wu, Yifang Qin, Taian Guo, Tao Zhe, Jiaru Tang, Zhiping Xiao, Weizhi Zhang, Ziyue Qiao, Wei Ju, Dongjie Wang, Xiao Luo, Philip S. Yu, and Ming Zhang, “PRISM: Partial-label Relational Inference with Spatial and Spectral Cues,” In International Conference on Learning Representations (ICLR), 2026.
  • Yidi Wang, Ziyue Qiao, Jiawei Gu, Xubin Zheng, Pengyang Wang, Xiaobing Pei, and Xiao Luo, “Out-of-Distribution Graph Models Merging,” In International Conference on Learning Representations (ICLR), 2026.
  • Yusheng Zhao, Qixin Zhang, Xiao Luo, Weizhi Zhang, Zhiping Xiao, Wei Ju, Philip S. Yu, and Ming Zhang, “Dynamic Text Bundling Supervision for Zero-Shot Inference on Text-Attributed Graphs,” In Annual Conference on Neural Information Processing Systems (NeurIPS), 2025.
  • Tianyu Liu, Tinyi Chi, Xiao Luo, and Hongyu Zhao, “BAITSAO: Building A Unified Model for Drug Synergy Analysis Powered by Large Language Models,” Nature Communications, 2025.
  • Junyu Luo, Yuhao Tang, Yiwei Fu, Xiao Luo, Zhizhuo Kou, Zhiping Xiao, Wei Ju, Wentao Zhang, and Ming Zhang, “Sparse Causal Discovery with Generative Intervention for Unsupervised Graph Domain Adaptation,” In International Conference on Machine Learning (ICML), 2025.
  • Guancheng Wan, Zijie Huang, Wanjia Zhao, Xiao Luo, Yizhou Sun, and Wei Wang, “Rethink GraphODE Generalization within Coupled Dynamical System,” In International Conference on Machine Learning (ICML), 2025.
  • Yifan Wang, Hourun Li, Ling Yue, Zhiping Xiao, Jia Yang, Changling Zhou, Wei Ju, Ming Zhang, and Xiao Luo, “DANCE: Dual Unbiased Expansion with Group-acquired Alignment for Out-of-distribution Graph Fairness Learning,” In International Conference on Machine Learning (ICML), 2025.
  • Ziyue Qiao, Qianyi Cai, Hao Dong, Jiawei Gu, Pengyang Wang, Meng Xiao, Xiao Luo, and Hui Xiong, “GCAL: Adapting Graph Models to Evolving Domain Shifts,” In International Conference on Machine Learning (ICML), 2025.
  • Yusheng Zhao, Qixin Zhang, Xiao Luo, Junyu Luo, Wei Ju, Zhiping Xiao, and Ming Zhang, “Test-time Adaptation on Graphs via Adaptive Subgraph-based Selection and Regularized Prototypes,” In International Conference on Machine Learning (ICML), 2025.
  • Huanhuan Wei, Xiao Luo, Hongyi Yu, Jinping Liang, Luning Yang, Lixing Lin, Alexandra Popa, and Xiting Yan, “Identifying Cellular Niches in Spatial Transcriptomics: An Investigation into the Capabilities of Large Language Models,” In The Annual Meeting of the Association for Computational Linguistics (ACL), 2025.
  • Yusheng Zhao, Xiao Luo, Haomin Wen, Zhiping Xiao, Wei Ju, Ming Zhang, “Embracing Large Language Models in Traffic Flow Forecasting,” In The Annual Meeting of the Association for Computational Linguistics Findings (ACL Findings), 2025.
  • Zhiyin Yu, Chao Zheng, Chong Chen, Xian-Sheng Hua, and Xiao Luo, “scRAG: Hybrid Retrieval-Augmented Generation for LLM-based Cross-Tissue Single-Cell Annotation,” In The Annual Meeting of the Association for Computational Linguistics Findings (ACL Findings), 2025.

Teaching

  • Fall 2026, STAT 451: Introduction to Machine Learning and Statistical Pattern Classification
  • Spring 2026, STAT 601: Statistical Methods I

Selected Awards and Honors

  • Chancellor's Award for Postdoctoral Research, UCLA
  • NeurIPS 2023 Workshop DLDE Best Paper Award
  • Institute for Digital Research and Education Postdoctoral Fellowship, UCLA
  • CIKM 2025 Best Paper Candidate

Selected Academic Services

Associate Editor / Editorial Board Member: BMC Bioinformatics (2023-), Pattern Recognition (2025-), IEEE Journal of Biomedical and Health Informatics (2025-), Transactions on Machine Learning Research (2025-), IEEE Transactions on Emerging Topics in Computational Intelligence (2025-), and IEEE Transactions on Circuits and Systems for Video Technology (2025-).

Area Chair: ACM MM 2024, ICML 2025, ACL ARR, ACM MM 2025, ECML-PKDD 2025, NeurIPS 2025, ICLR 2026, CVPR 2026, ICML 2026, ECML-PKDD 2026, KDD 2026, and KDD 2026 AI4Science Track.

Senior Program Committee: IJCAI 2025, CIKM 2025, AAAI 2026, and IJCAI 2026.

Recognition: Distinguished Area Chair Certificate, ECML-PKDD 2025.

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